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cPLA(2)α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation
As a regulator of cellular inflammation and proliferation, cytosolic phospholipase A(2) α (cPLA(2)α) is a promising therapeutic target for psoriasis; indeed, the cPLA(2)α inhibitor AVX001 has shown efficacy against plaque psoriasis in a phase I/IIa clinical trial. To improve our understanding of the...
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| Veröffentlicht in: | Biomolecules |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7600040/ https://ncbi.nlm.nih.gov/pubmed/33023184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10101402 |
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