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Data on the generation of two Nr2e3 mouse models by CRISPR / Cas9D10A nickase
NR2E3 encodes an orphan nuclear receptor that plays a dual function as both transcriptional activator and repressor in photoreceptors, being necessary for cone fate inhibition as well as rod differentiation and homeostasis. Mutations in this gene cause retinitis pigmentosa (RP), enhanced S cone synd...
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| Publicado no: | Data Brief |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7599427/ https://ncbi.nlm.nih.gov/pubmed/33163596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dib.2020.106447 |
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