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A cyclin-dependent kinase, CDK11/p58, represses cap-dependent translation during mitosis

During mitosis, translation of most mRNAs is strongly repressed; none of the several explanatory hypotheses suggested can fully explain the molecular basis of this phenomenon. Here we report that cyclin-dependent CDK11/p58—a serine/threonine kinase abundantly expressed during M phase—represses overa...

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Détails bibliographiques
Publié dans:Cell Mol Life Sci
Auteurs principaux: An, Sihyeon, Kwon, Oh Sung, Yu, Jinbae, Jang, Sung Key
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599166/
https://ncbi.nlm.nih.gov/pubmed/32030451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03436-3
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