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Cap-dependent translation is mediated by ‘RNA looping’ rather than ‘ribosome scanning’
The 40S ribosomal subunit cannot directly recognize the start codon of eukaryotic mRNAs. Instead, it recognizes the start codon after its association with the 5′-cap structure via translation initiation factors. Base-by-base inspection of the 5′UTR by a scanning ribosome is the generally accepted hy...
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| Publicado no: | RNA Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4829323/ https://ncbi.nlm.nih.gov/pubmed/26515582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1107700 |
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