The efficacy of aspirin and metformin combination therapy in patients with rectal aberrant crypt foci: a double-blinded randomized controlled trial

BACKGROUND: The incidence and mortality rates of colorectal cancer (CRC) continue to increase worldwide. Therefore, new preventive strategies are needed to lower the burden of this disease. Previous studies reported that aspirin could suppress the development of sporadic colorectal adenoma. In addit...

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Vydáno v:BMC Cancer
Hlavní autoři: Higurashi, Takuma, Arimoto, Jun, Ashikari, Keiichi, Takatsu, Tomohiro, Misawa, Noboru, Yoshihara, Tsutomu, Matsuura, Tetsuya, Fuyuki, Akiko, Ohkubo, Hidenori, Nakajima, Atsushi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Study Protocol
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599108/
https://ncbi.nlm.nih.gov/pubmed/33121471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07564-z
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