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The efficacy of aspirin and metformin combination therapy in patients with rectal aberrant crypt foci: a double-blinded randomized controlled trial

BACKGROUND: The incidence and mortality rates of colorectal cancer (CRC) continue to increase worldwide. Therefore, new preventive strategies are needed to lower the burden of this disease. Previous studies reported that aspirin could suppress the development of sporadic colorectal adenoma. In addit...

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Dettagli Bibliografici
Pubblicato in:BMC Cancer
Autori principali: Higurashi, Takuma, Arimoto, Jun, Ashikari, Keiichi, Takatsu, Tomohiro, Misawa, Noboru, Yoshihara, Tsutomu, Matsuura, Tetsuya, Fuyuki, Akiko, Ohkubo, Hidenori, Nakajima, Atsushi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599108/
https://ncbi.nlm.nih.gov/pubmed/33121471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07564-z
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