The efficacy of aspirin and metformin combination therapy in patients with rectal aberrant crypt foci: a double-blinded randomized controlled trial

BACKGROUND: The incidence and mortality rates of colorectal cancer (CRC) continue to increase worldwide. Therefore, new preventive strategies are needed to lower the burden of this disease. Previous studies reported that aspirin could suppress the development of sporadic colorectal adenoma. In addit...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Higurashi, Takuma, Arimoto, Jun, Ashikari, Keiichi, Takatsu, Tomohiro, Misawa, Noboru, Yoshihara, Tsutomu, Matsuura, Tetsuya, Fuyuki, Akiko, Ohkubo, Hidenori, Nakajima, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599108/
https://ncbi.nlm.nih.gov/pubmed/33121471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07564-z
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