The efficacy of aspirin and metformin combination therapy in patients with rectal aberrant crypt foci: a double-blinded randomized controlled trial

BACKGROUND: The incidence and mortality rates of colorectal cancer (CRC) continue to increase worldwide. Therefore, new preventive strategies are needed to lower the burden of this disease. Previous studies reported that aspirin could suppress the development of sporadic colorectal adenoma. In addit...

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Publicado en:BMC Cancer
Autores principales: Higurashi, Takuma, Arimoto, Jun, Ashikari, Keiichi, Takatsu, Tomohiro, Misawa, Noboru, Yoshihara, Tsutomu, Matsuura, Tetsuya, Fuyuki, Akiko, Ohkubo, Hidenori, Nakajima, Atsushi
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Study Protocol
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599108/
https://ncbi.nlm.nih.gov/pubmed/33121471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07564-z
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