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Clustering and Fibril Formation during GNNQQNY Aggregation: A Molecular Dynamics Study

The precise kinetic pathways of peptide clustering and fibril formation are not fully understood. Here we study the initial clustering kinetics and transient cluster morphologies during aggregation of the heptapeptide fragment GNNQQNY from the yeast prion protein Sup35. We use a mid-resolution coars...

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Foilsithe in:Biomolecules
Main Authors: Szała-Mendyk, Beata, Molski, Andrzej
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598727/
https://ncbi.nlm.nih.gov/pubmed/32987720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10101362
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