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Boosting NAD level suppresses inflammatory activation of PBMCs in heart failure

BACKGROUND: While mitochondria play an important role in innate immunity, the relationship between mitochondrial dysfunction and inflammation in heart failure (HF) is poorly understood. In this study we aimed to investigate the mechanistic link between mitochondrial dysfunction and inflammatory acti...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Zhou, Bo, Wang, Dennis Ding-Hwa, Qiu, Yanhua, Airhart, Sophia, Liu, Yaxin, Stempien-Otero, April, O’Brien, Kevin D., Tian, Rong
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598081/
https://ncbi.nlm.nih.gov/pubmed/32790648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138538
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