Boosting NAD level suppresses inflammatory activation of PBMCs in heart failure

BACKGROUND: While mitochondria play an important role in innate immunity, the relationship between mitochondrial dysfunction and inflammation in heart failure (HF) is poorly understood. In this study we aimed to investigate the mechanistic link between mitochondrial dysfunction and inflammatory acti...

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Publicat a:J Clin Invest
Autors principals: Zhou, Bo, Wang, Dennis Ding-Hwa, Qiu, Yanhua, Airhart, Sophia, Liu, Yaxin, Stempien-Otero, April, O’Brien, Kevin D., Tian, Rong
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Clinical Medicine
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598081/
https://ncbi.nlm.nih.gov/pubmed/32790648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138538
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