Boosting NAD level suppresses inflammatory activation of PBMCs in heart failure

BACKGROUND: While mitochondria play an important role in innate immunity, the relationship between mitochondrial dysfunction and inflammation in heart failure (HF) is poorly understood. In this study we aimed to investigate the mechanistic link between mitochondrial dysfunction and inflammatory acti...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Zhou, Bo, Wang, Dennis Ding-Hwa, Qiu, Yanhua, Airhart, Sophia, Liu, Yaxin, Stempien-Otero, April, O’Brien, Kevin D., Tian, Rong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Clinical Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598081/
https://ncbi.nlm.nih.gov/pubmed/32790648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138538
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