Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma

Angiosarcomas are rare, clinically aggressive tumors with limited treatment options and a dismal prognosis. We analyzed angiosarcomas from 68 patients, integrating information from multiomic sequencing, NanoString immuno-oncology profiling, and multiplex immunohistochemistry and immunofluorescence f...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Chan, Jason Yongsheng, Lim, Jing Quan, Yeong, Joe, Ravi, Vinod, Guan, Peiyong, Boot, Arnoud, Tay, Timothy Kwang Yong, Selvarajan, Sathiyamoorthy, Md Nasir, Nur Diyana, Loh, Jie Hua, Ong, Choon Kiat, Huang, Dachuan, Tan, Jing, Li, Zhimei, Ng, Cedric Chuan-Young, Tan, Thuan Tong, Masuzawa, Mikio, Sung, Ken Wing-Kin, Farid, Mohamad, Quek, Richard Hong Hui, Tan, Ngian Chye, Teo, Melissa Ching Ching, Rozen, Steven George, Tan, Patrick, Futreal, Andrew, Teh, Bin Tean, Soo, Khee Chee
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598061/
https://ncbi.nlm.nih.gov/pubmed/33016928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI139080
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