Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma

Angiosarcomas are rare, clinically aggressive tumors with limited treatment options and a dismal prognosis. We analyzed angiosarcomas from 68 patients, integrating information from multiomic sequencing, NanoString immuno-oncology profiling, and multiplex immunohistochemistry and immunofluorescence f...

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Vydáno v:J Clin Invest
Hlavní autoři: Chan, Jason Yongsheng, Lim, Jing Quan, Yeong, Joe, Ravi, Vinod, Guan, Peiyong, Boot, Arnoud, Tay, Timothy Kwang Yong, Selvarajan, Sathiyamoorthy, Md Nasir, Nur Diyana, Loh, Jie Hua, Ong, Choon Kiat, Huang, Dachuan, Tan, Jing, Li, Zhimei, Ng, Cedric Chuan-Young, Tan, Thuan Tong, Masuzawa, Mikio, Sung, Ken Wing-Kin, Farid, Mohamad, Quek, Richard Hong Hui, Tan, Ngian Chye, Teo, Melissa Ching Ching, Rozen, Steven George, Tan, Patrick, Futreal, Andrew, Teh, Bin Tean, Soo, Khee Chee
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598061/
https://ncbi.nlm.nih.gov/pubmed/33016928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI139080
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