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The rebirth of the contact pathway: a new therapeutic target

PURPOSE OF REVIEW: Anticoagulation with vitamin-K antagonists or direct oral anticoagulants is associated with a significant risk of bleeding. There is a major effort underway to develop antithrombotic drugs that have a smaller impact on hemostasis. The plasma contact proteins factor XI (FXI) and fa...

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Bibliografiske detaljer
Udgivet i:Curr Opin Hematol
Main Authors: Srivastava, Priyanka, Gailani, David
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596882/
https://ncbi.nlm.nih.gov/pubmed/32740037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000603
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