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Macrophage hypophagia as a mechanism of innate immune exhaustion in mAb-induced cell clearance
Macrophage antibody (Ab)-dependent cellular phagocytosis (ADCP) is a major cytotoxic mechanism for both therapeutic unconjugated monoclonal Abs (mAbs) such as rituximab and Ab-induced hemolytic anemia and immune thrombocytopenia. Here, we studied the mechanisms controlling the rate and capacity of m...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7596847/ https://ncbi.nlm.nih.gov/pubmed/32556153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005571 |
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