Repression of the B cell identity factor Pax5 is not required for plasma cell development

B cell and plasma cell fates are controlled by different transcriptional networks, as exemplified by the mutually exclusive expression and cross-antagonism of the B cell identity factor Pax5 and the plasma cell regulator Blimp1. It has been postulated that repression of Pax5 by Blimp1 is essential f...

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Vydáno v:J Exp Med
Hlavní autoři: Liu, Grace J., Jaritz, Markus, Wöhner, Miriam, Agerer, Benedikt, Bergthaler, Andreas, Malin, Stephen G., Busslinger, Meinrad
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596824/
https://ncbi.nlm.nih.gov/pubmed/32780801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200147
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