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Modified aptamers as reagents to characterize recombinant human erythropoietin products

Reliable and reproducible monitoring of the conformational state of therapeutic protein products remains an unmet technological need. This need is amplified by the increasing number of biosimilars entering the drug development pipeline as many branded biologics are reaching the end of their market e...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jankowski, Wojciech, Lagassé, H. A. Daniel, Chang, William C., McGill, Joseph, Jankowska, Katarzyna I., Gelinas, Amy D., Janjic, Nebojsa, Sauna, Zuben E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596557/
https://ncbi.nlm.nih.gov/pubmed/33122796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75713-2
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