Re-engineering Antimicrobial Peptides into Oncolytics Targeting Drug-Resistant Ovarian Cancers

INTRODUCTION: Bacteria and cancer cells share a common trait—both possess an electronegative surface that distinguishes them from healthy mammalian counterparts. This opens opportunities to repurpose antimicrobial peptides (AMPs), which are cationic amphiphiles that kill bacteria by disrupting their...

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Udgivet i:Cell Mol Bioeng
Main Authors: Aronson, Matthew R., Dahl, Erika S., Halle, Jacob A., Simonson, Andrew W., Gogal, Rose A., Glick, Adam B., Aird, Katherine M., Medina, Scott H.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
2020 CMBE Young Innovators issue
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596148/
https://ncbi.nlm.nih.gov/pubmed/33184577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-020-00626-z
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