Tissue-Engineered Stromal Reticula to Study Lymph Node Fibroblastic Reticular Cells in Type I Diabetes

INTRODUCTION: Fibroblastic reticular cells (FRCs) support and remodel the lymph node (LN), express and present self-antigens to T cells to promote tolerance. In Type 1 diabetes (T1D), decrease in FRC frequency and in their expression of T1D-related self-antigens may hinder tolerogenic engagement of...

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Udgivet i:Cell Mol Bioeng
Main Authors: Gonzalez Badillo, Freddy, Zisi Tegou, Flavia, Masina, Riccardo, Wright, Shane, Scully, Mackenzie, Harwell, Laura, Lupp, Michael, Postigo-Fernandez, Jorge, Creusot, Remi J., Tomei, Alice A.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
2020 CMBE Young Innovators issue
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596159/
https://ncbi.nlm.nih.gov/pubmed/33184575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-020-00627-y
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