Re-engineering Antimicrobial Peptides into Oncolytics Targeting Drug-Resistant Ovarian Cancers

INTRODUCTION: Bacteria and cancer cells share a common trait—both possess an electronegative surface that distinguishes them from healthy mammalian counterparts. This opens opportunities to repurpose antimicrobial peptides (AMPs), which are cationic amphiphiles that kill bacteria by disrupting their...

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Detalhes bibliográficos
Publicado no:Cell Mol Bioeng
Main Authors: Aronson, Matthew R., Dahl, Erika S., Halle, Jacob A., Simonson, Andrew W., Gogal, Rose A., Glick, Adam B., Aird, Katherine M., Medina, Scott H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
2020 CMBE Young Innovators issue
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596148/
https://ncbi.nlm.nih.gov/pubmed/33184577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-020-00626-z
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