Ultra-deformable liposomes containing terpenes (terpesomes) loaded fenticonazole nitrate for treatment of vaginal candidiasis: Box-Behnken design optimization, comparative ex vivo and in vivo studies

Fenticonazole nitrate (FTN) is a potent antifungal drug adopted in the treatment of vaginal candidiasis. It has inadequate aqueous solubility hence, novel ultra-deformable liposomes ‘Terpesomes’ (TPs) were developed that might prevail over FTN poor solubility besides TPs might abstain the obstacles...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Albash, Rofida, Elmahboub, Yasmina, Baraka, Kholoud, Abdellatif, Menna M., Alaa-Eldin, Ahmed Adel
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594706/
https://ncbi.nlm.nih.gov/pubmed/33108907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2020.1837295
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