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Design and Synthesis of Helical N-Terminal l-Prolyl Oligopeptides Possessing Hydrocarbon Stapling

We designed and synthesized helical short oligopeptides with an l-proline on the N-terminus and hydrocarbon stapling on the side chain. Side-chain stapling is a frequently used method for the development of biologically active peptides. Side-chain stapling can stabilize the secondary structures of p...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Ueda, Atsushi, Higuchi, Mei, Sato, Kazuki, Umeno, Tomohiro, Tanaka, Masakazu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594088/
https://ncbi.nlm.nih.gov/pubmed/33066194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204667
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