Caricamento...

N-Alkylated Iminosugar Based Ligands: Synthesis and Inhibition of Human Lysosomal β-Glucocerebrosidase

The scope of a series of N-alkylated iminosugar based inhibitors in the d-gluco as well as d-xylo configuration towards their interaction with human lysosomal β-glucocerebrosidase has been evaluated. A versatile synthetic toolbox has been developed for the synthesis of N-alkylated iminosugar scaffol...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Molecules
Autori principali: Wolfsgruber, Andreas, Thonhofer, Martin, Weber, Patrick, Nasseri, Seyed A., Fischer, Roland, Schalli, Michael, Stütz, Arnold E., Withers, Stephen G., Wrodnigg, Tanja M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594070/
https://ncbi.nlm.nih.gov/pubmed/33050585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204618
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !