Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands

A series of 27 compounds of general structure 2,3-dihydro-benzo[1,4]oxazin-4-yl)-2-{4-[3-(1H-3indolyl)-propyl]-1-piperazinyl}-ethanamides, Series I: 7(a–o) and (2-{4-[3-(1H-3-indolyl)-propyl]-1-piperazinyl}-acetylamine)-N-(2-morfolin-4-yl-ethyl)-fluorinated benzamides Series II: 13(a–l) were synthes...

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Publicado no:Molecules
Main Authors: Cerda-Cavieres, Christopher, Quiroz, Gabriel, Iturriaga-Vásquez, Patricio, Rodríguez-Lavado, Julio, Alarcón-Espósito, Jazmín, Saitz, Claudio, Pessoa-Mahana, Carlos D., Chung, Hery, Araya-Maturana, Ramiro, Mella-Raipán, Jaime, Cabezas, David, Ojeda-Gómez, Claudia, Reyes-Parada, Miguel, Pessoa-Mahana, Hernán
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594025/
https://ncbi.nlm.nih.gov/pubmed/33050524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204614
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