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3D-QSAR/CoMFA-Based Structure-Affinity/Selectivity Relationships of Aminoalkylindoles in the Cannabinoid CB1 and CB2 Receptors

A 3D-QSAR (CoMFA) study was performed in an extensive series of aminoalkylindoles derivatives with affinity for the cannabinoid receptors CB1 and CB2. The aim of the present work was to obtain structure-activity relationships of the aminoalkylindole family in order to explain the affinity and select...

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Dettagli Bibliografici
Pubblicato in:Molecules
Autori principali: Mella-Raipán, Jaime, Hernández-Pino, Santiago, Morales-Verdejo, César, Pessoa-Mahana, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270810/
https://ncbi.nlm.nih.gov/pubmed/24603555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19032842
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