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3D-QSAR/CoMFA-Based Structure-Affinity/Selectivity Relationships of Aminoalkylindoles in the Cannabinoid CB1 and CB2 Receptors

A 3D-QSAR (CoMFA) study was performed in an extensive series of aminoalkylindoles derivatives with affinity for the cannabinoid receptors CB1 and CB2. The aim of the present work was to obtain structure-activity relationships of the aminoalkylindole family in order to explain the affinity and select...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Mella-Raipán, Jaime, Hernández-Pino, Santiago, Morales-Verdejo, César, Pessoa-Mahana, David
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270810/
https://ncbi.nlm.nih.gov/pubmed/24603555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19032842
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