The Impact of BKI-1294 Therapy in Mice Infected With the Apicomplexan Parasite Neospora caninum and Re-infected During Pregnancy

Exposure of Neospora caninum tachyzoites to BKI-1294 in vitro results in the formation of long-lived multinucleated complexes (MNCs). However, in vivo treatment of BALB/c mice with BKI-1294 shortly after N. caninum infection during pregnancy was safe and profoundly reduced pup mortality and vertical...

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Bibliographic Details
Published in:Front Vet Sci
Main Authors: Winzer, Pablo, Imhof, Dennis, Anghel, Nicoleta, Ritler, Dominic, Müller, Joachim, Boubaker, Ghalia, Aguado-Martinez, Adriana, Ortega-Mora, Luis-Miguel, Ojo, Kayode K., VanVoorhis, Wesley C., Hemphill, Andrew
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Veterinary Science
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593410/
https://ncbi.nlm.nih.gov/pubmed/33195616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2020.587570
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