Buparvaquone is active against Neospora caninum in vitro and in experimentally infected mice

The naphthoquinone buparvaquone is currently the only drug used against theileriosis. Here, the effects of buparvaquone were investigated in vitro and in an experimental mouse model for Neospora caninum infection. In 4-day proliferation assays, buparvaquone efficiently inhibited N. caninum tachyzoit...

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Detalhes bibliográficos
Main Authors: Joachim Müller, Adriana Aguado-Martinez, Vera Manser, Vreni Balmer, Pablo Winzer, Dominic Ritler, Isabel Hostettler, David Arranz-Solís, Luis Ortega-Mora, Andrew Hemphill
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015-04-01
Colecção:International Journal for Parasitology: Drugs and Drug Resistance
Assuntos:
Neospora caninum
Neosporosis
Buparvaquone
Electron microscopy
Cerebral infection
Real time PCR
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211320715000032
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