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Exploring chromosomal structural heterogeneity across multiple cell lines
Using computer simulations, we generate cell-specific 3D chromosomal structures and compare them to recently published chromatin structures obtained through microscopy. We demonstrate using machine learning and polymer physics simulations that epigenetic information can be used to predict the struct...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7593087/ https://ncbi.nlm.nih.gov/pubmed/33047670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60312 |
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