Aberrant Differentiation of Human Pluripotent Stem Cell-Derived Kidney Precursor Cells inside Mouse Vascularized Bioreactors

BACKGROUND: Numerous studies have documented the in vitro differentiation of human pluripotent stem cells (hPSCs) into kidney cells. Fewer studies have followed the fates of such kidney precursor cells (KPCs) inside animals, a more life-like setting. Here, we tested the hypothesis that implanting hP...

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Veröffentlicht in:Nephron Clin Pract
Hauptverfasser: Ranjzad, Parisa, Jinks, Jessica, Salahi, Amir P., Bantounas, Ioannis, Derby, Brian, Kimber, Susan J., Woolf, Adrian S., Wong, Jason K.F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2020
Schlagworte:
Experimental Nephrology and Genetics: Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592943/
https://ncbi.nlm.nih.gov/pubmed/32756058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000509425
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