Generation of Functioning Nephrons by Implanting Human Pluripotent Stem Cell-Derived Kidney Progenitors

Human pluripotent stem cells (hPSCs) hold great promise for understanding kidney development and disease. We reproducibly differentiated three genetically distinct wild-type hPSC lines to kidney precursors that underwent rudimentary morphogenesis in vitro. They expressed nephron and collecting duct...

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Vydáno v:Stem Cell Reports
Hlavní autoři: Bantounas, Ioannis, Ranjzad, Parisa, Tengku, Faris, Silajdžić, Edina, Forster, Duncan, Asselin, Marie-Claude, Lewis, Philip, Lennon, Rachel, Plagge, Antonius, Wang, Qi, Woolf, Adrian S., Kimber, Susan J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918196/
https://ncbi.nlm.nih.gov/pubmed/29429961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.008
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