Aberrant Differentiation of Human Pluripotent Stem Cell-Derived Kidney Precursor Cells inside Mouse Vascularized Bioreactors

BACKGROUND: Numerous studies have documented the in vitro differentiation of human pluripotent stem cells (hPSCs) into kidney cells. Fewer studies have followed the fates of such kidney precursor cells (KPCs) inside animals, a more life-like setting. Here, we tested the hypothesis that implanting hP...

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Udgivet i:Nephron Clin Pract
Main Authors: Ranjzad, Parisa, Jinks, Jessica, Salahi, Amir P., Bantounas, Ioannis, Derby, Brian, Kimber, Susan J., Woolf, Adrian S., Wong, Jason K.F.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2020
Fag:
Experimental Nephrology and Genetics: Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592943/
https://ncbi.nlm.nih.gov/pubmed/32756058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000509425
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