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Combination of radiotherapy and suppression of Tregs enhances abscopal antitumor effect and inhibits metastasis in rectal cancer

BACKGROUND: Distant metastasis is the major cause of mortality in patients with locally advanced rectal cancer (LARC) following neoadjuvant chemoradiotherapy. Local radiotherapy can trigger an abscopal response to metastatic tumor cells. However, the abscopal effect is a rare event. CD4+ regulatory...

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書誌詳細
出版年:J Immunother Cancer
主要な著者: Ji, Dengbo, Song, Can, Li, Yongheng, Xia, Jinhong, Wu, Yanjing, Jia, Jinying, Cui, Xinxin, Yu, Songmao, Gu, Jin
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Publishing Group 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592256/
https://ncbi.nlm.nih.gov/pubmed/33106387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000826
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