Combination of radiotherapy and suppression of Tregs enhances abscopal antitumor effect and inhibits metastasis in rectal cancer

BACKGROUND: Distant metastasis is the major cause of mortality in patients with locally advanced rectal cancer (LARC) following neoadjuvant chemoradiotherapy. Local radiotherapy can trigger an abscopal response to metastatic tumor cells. However, the abscopal effect is a rare event. CD4+ regulatory...

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Bibliografiske detaljer
Udgivet i:J Immunother Cancer
Main Authors: Ji, Dengbo, Song, Can, Li, Yongheng, Xia, Jinhong, Wu, Yanjing, Jia, Jinying, Cui, Xinxin, Yu, Songmao, Gu, Jin
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2020
Fag:
Basic Tumor Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592256/
https://ncbi.nlm.nih.gov/pubmed/33106387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000826
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