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Reovirus σ3 Protein Limits Interferon Expression and Cell Death Induction

Induction of necroptosis by mammalian reovirus requires both type I interferon (IFN)-signaling and viral replication events that lead to production of progeny genomic double-stranded RNA (dsRNA). The reovirus outer capsid protein μ1 negatively regulates reovirus-induced necroptosis by limiting RNA s...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Roebke, Katherine E., Guo, Yingying, Parker, John S. L., Danthi, Pranav
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592210/
https://ncbi.nlm.nih.gov/pubmed/32847863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01485-20
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