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Reovirus σ3 Protein Limits Interferon Expression and Cell Death Induction

Induction of necroptosis by mammalian reovirus requires both type I interferon (IFN)-signaling and viral replication events that lead to production of progeny genomic double-stranded RNA (dsRNA). The reovirus outer capsid protein μ1 negatively regulates reovirus-induced necroptosis by limiting RNA s...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Roebke, Katherine E., Guo, Yingying, Parker, John S. L., Danthi, Pranav
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592210/
https://ncbi.nlm.nih.gov/pubmed/32847863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01485-20
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