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Cell Entry-Independent Role for the Reovirus μ1 Protein in Regulating Necroptosis and the Accumulation of Viral Gene Products

The reovirus outer capsid protein μ1 regulates cell death in infected cells. To distinguish between the roles of incoming, capsid-associated, and newly synthesized μ1, we used small interfering RNA (siRNA)-mediated knockdown. Loss of newly synthesized μ1 protein does not affect apoptotic cell death...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Roebke, Katherine E., Danthi, Pranav
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532083/
https://ncbi.nlm.nih.gov/pubmed/30894465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00199-19
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