Viral RNA at Two Stages of Reovirus Infection Is Required for the Induction of Necroptosis

Necroptosis, a regulated form of necrotic cell death, requires the activation of the RIP3 kinase. Here, we identify that infection of host cells with reovirus can result in necroptosis. We find that necroptosis requires sensing of the genomic RNA within incoming virus particles via cytoplasmic RNA s...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Berger, Angela K., Hiller, Bradley E., Thete, Deepti, Snyder, Anthony J., Perez, Encarnacion, Upton, Jason W., Danthi, Pranav
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331789/
https://ncbi.nlm.nih.gov/pubmed/28077640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02404-16
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi