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Conformational Changes Required for Reovirus Cell Entry are Sensitive to pH

During cell entry, reovirus particles disassemble to generate ISVPs. ISVPs undergo conformational changes to form ISVP* and this conversion is required for membrane penetration. In tissues where ISVP formation occurs within endosomes, ISVP-to-ISVP* conversion occurs at low pH. In contrast, in tissue...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Thete, Deepti, Danthi, Pranav
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516592/
https://ncbi.nlm.nih.gov/pubmed/26004253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.04.025
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