Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression

Tumor necrosis commonly exists and predicts poor prognoses in many cancers. Although it is thought to result from chronic ischemia, the underlying nature and mechanisms driving the involved cell death remain obscure. Here, we show that necrosis in glioblastoma (GBM) involves neutrophil-triggered fer...

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Pubblicato in:Nat Commun
Autori principali: Yee, Patricia P., Wei, Yiju, Kim, Soo-Yeon, Lu, Tong, Chih, Stephen Y., Lawson, Cynthia, Tang, Miaolu, Liu, Zhijun, Anderson, Benjamin, Thamburaj, Krishnamoorthy, Young, Megan M., Aregawi, Dawit G., Glantz, Michael J., Zacharia, Brad E., Specht, Charles S., Wang, Hong-Gang, Li, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591536/
https://ncbi.nlm.nih.gov/pubmed/33110073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19193-y
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