Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression

Tumor necrosis commonly exists and predicts poor prognoses in many cancers. Although it is thought to result from chronic ischemia, the underlying nature and mechanisms driving the involved cell death remain obscure. Here, we show that necrosis in glioblastoma (GBM) involves neutrophil-triggered fer...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yee, Patricia P., Wei, Yiju, Kim, Soo-Yeon, Lu, Tong, Chih, Stephen Y., Lawson, Cynthia, Tang, Miaolu, Liu, Zhijun, Anderson, Benjamin, Thamburaj, Krishnamoorthy, Young, Megan M., Aregawi, Dawit G., Glantz, Michael J., Zacharia, Brad E., Specht, Charles S., Wang, Hong-Gang, Li, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591536/
https://ncbi.nlm.nih.gov/pubmed/33110073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19193-y
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