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TMIC-50. HYPERACTIVATING THE HIPPO PATHWAY EFFECTOR TAZ DISTORTS THE TUMOR MICROENVIRONMENT, PROMOTES TUMOR-ENTRAINED NEUTROPHIL INFILTRATION, AND PHENOCOPIES MESENCHYMAL-GLIOBLASTOMA
Glioblastoma (GBM), the deadliest and most common primary CNS malignancy in adults, is highly heterogeneous with variable prognoses and treatment responses. The molecular underpinnings for such variability remain largely unclear. Mesenchymal (MES)-GBMs, associated with poorest prognosis and highest...
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| Publicado no: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217124/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1109 |
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