Tumour-associated neutrophils orchestrate intratumoural IL-8-driven immune evasion through Jagged2 activation in ovarian cancer

BACKGROUND: Tumour associated neutrophils (TANs) play a controversial role in regulating immune surveillance and immune evasion in various malignancies. Here, we investigated the relevance of TANs with the prognosis and immune microenvironment of epithelial ovarian cancer (EOC). METHODS: We characte...

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Vydáno v:Br J Cancer
Hlavní autoři: Yang, Moran, Zhang, Guodong, Wang, Yiying, He, Mengdi, Xu, Qing, Lu, Jiaqi, Liu, Haiou, Xu, Congjian
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591527/
https://ncbi.nlm.nih.gov/pubmed/32778818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-1026-0
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