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CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer
BACKGROUND: Most patients with high-grade serous ovarian cancer (HGSC) lack an effective response to immune checkpoint blockade, highlighting the need for more knowledge about what is required for successful treatment. As follicular cytotoxic CXCR5(+)CD8(+) T cells are maintained by reinvigoration b...
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| Pubblicato in: | J Immunother Cancer |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMJ Publishing Group
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7813306/ https://ncbi.nlm.nih.gov/pubmed/33452206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001136 |
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