Serum indoxyl sulfate concentrations associate with progression of chronic kidney disease in children

The uremic toxins indoxyl sulfate (IS) and p-cresyl sulfate (pCS) accumulate in patients with chronic kidney disease (CKD) as a consequence of altered gut microbiota metabolism and a decline in renal excretion. Despite of solid experimental evidence for nephrotoxic effects, the impact of uremic toxi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Holle, Johannes, Kirchner, Marietta, Okun, Jürgen, Bayazit, Aysun K., Obrycki, Lukasz, Canpolat, Nur, Bulut, Ipek Kaplan, Azukaitis, Karolis, Duzova, Ali, Ranchin, Bruno, Shroff, Rukshana, Candan, Cengiz, Oh, Jun, Klaus, Günter, Lugani, Francesca, Gimpel, Charlotte, Büscher, Rainer, Yilmaz, Alev, Baskin, Esra, Erdogan, Hakan, Zaloszyc, Ariane, Özcelik, Gül, Drozdz, Dorota, Jankauskiene, Augustina, Nobili, Francois, Melk, Anette, Querfeld, Uwe, Schaefer, Franz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591021/
https://ncbi.nlm.nih.gov/pubmed/33108385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240446
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