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Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation
The identification of the peptide epitopes presented by major histocompatibility complex class II (MHCII) molecules that drive the CD4 T cell component of autoimmune diseases has presented a formidable challenge over several decades. In type 1 diabetes (T1D), recent insight into this problem has com...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7590512/ https://ncbi.nlm.nih.gov/pubmed/33095259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192135 |
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