One‐Pot Synthesis of Chiral N‐Arylamines by Combining Biocatalytic Aminations with Buchwald–Hartwig N‐Arylation

The combination of biocatalysis and chemo‐catalysis increasingly offers chemists access to more diverse chemical architectures. Here, we describe the combination of a toolbox of chiral‐amine‐producing biocatalysts with a Buchwald–Hartwig cross‐coupling reaction, affording a variety of α‐chiral anili...

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Detalles Bibliográficos
Publicado en:Angew Chem Int Ed Engl
Autores principales: Cosgrove, Sebastian C., Thompson, Matthew P., Ahmed, Syed T., Parmeggiani, Fabio, Turner, Nicholas J.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590080/
https://ncbi.nlm.nih.gov/pubmed/32628797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006246
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