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One‐Pot Synthesis of Chiral N‐Arylamines by Combining Biocatalytic Aminations with Buchwald–Hartwig N‐Arylation

The combination of biocatalysis and chemo‐catalysis increasingly offers chemists access to more diverse chemical architectures. Here, we describe the combination of a toolbox of chiral‐amine‐producing biocatalysts with a Buchwald–Hartwig cross‐coupling reaction, affording a variety of α‐chiral anili...

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Bibliografske podrobnosti
izdano v:Angew Chem Int Ed Engl
Main Authors: Cosgrove, Sebastian C., Thompson, Matthew P., Ahmed, Syed T., Parmeggiani, Fabio, Turner, Nicholas J.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590080/
https://ncbi.nlm.nih.gov/pubmed/32628797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006246
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