One‐Pot Synthesis of Chiral N‐Arylamines by Combining Biocatalytic Aminations with Buchwald–Hartwig N‐Arylation

The combination of biocatalysis and chemo‐catalysis increasingly offers chemists access to more diverse chemical architectures. Here, we describe the combination of a toolbox of chiral‐amine‐producing biocatalysts with a Buchwald–Hartwig cross‐coupling reaction, affording a variety of α‐chiral anili...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Cosgrove, Sebastian C., Thompson, Matthew P., Ahmed, Syed T., Parmeggiani, Fabio, Turner, Nicholas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590080/
https://ncbi.nlm.nih.gov/pubmed/32628797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006246
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