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Mifepristone Decreases Chronic Voluntary Ethanol Consumption in Rhesus Macaques
The efficacy of short-term treatment with mifepristone (MIFE), a high-affinity, nonselective glucocorticoid receptor antagonist, to reduce ethanol drinking was tested in a rhesus macaque model. Stable individual daily ethanol intakes were established, ranging from 1.6 to 4.0 g/kg per day (n = 9 monk...
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| Publicado no: | J Pharmacol Exp Ther |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7590013/ https://ncbi.nlm.nih.gov/pubmed/32873623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.000169 |
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