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Impact of Polyallylamine Hydrochloride on Gene Expression and Karyotypic Stability of Multidrug Resistant Transformed Cells

The synthetic polymer, polyallylamine hydrochloride (PAA), is found in a variety of applications in biotechnology and medicine. It is used in gene and siRNA transfer, to form microcapsules for targeted drug delivery to damaged and tumor cells. Conventional chemotherapy often does not kill all cancer...

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Vydáno v:Cells
Hlavní autoři: Alekseenko, Larisa, Shilina, Mariia, Kozhukharova, Irina, Lyublinskaya, Olga, Fridlyanskaya, Irina, Nikolsky, Nikolay, Grinchuk, Tatiana
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589997/
https://ncbi.nlm.nih.gov/pubmed/33096691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102332
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