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Impact of Polyallylamine Hydrochloride on Gene Expression and Karyotypic Stability of Multidrug Resistant Transformed Cells

The synthetic polymer, polyallylamine hydrochloride (PAA), is found in a variety of applications in biotechnology and medicine. It is used in gene and siRNA transfer, to form microcapsules for targeted drug delivery to damaged and tumor cells. Conventional chemotherapy often does not kill all cancer...

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Publicado en:Cells
Main Authors: Alekseenko, Larisa, Shilina, Mariia, Kozhukharova, Irina, Lyublinskaya, Olga, Fridlyanskaya, Irina, Nikolsky, Nikolay, Grinchuk, Tatiana
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589997/
https://ncbi.nlm.nih.gov/pubmed/33096691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102332
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