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Impact of Polyallylamine Hydrochloride on Gene Expression and Karyotypic Stability of Multidrug Resistant Transformed Cells

The synthetic polymer, polyallylamine hydrochloride (PAA), is found in a variety of applications in biotechnology and medicine. It is used in gene and siRNA transfer, to form microcapsules for targeted drug delivery to damaged and tumor cells. Conventional chemotherapy often does not kill all cancer...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Alekseenko, Larisa, Shilina, Mariia, Kozhukharova, Irina, Lyublinskaya, Olga, Fridlyanskaya, Irina, Nikolsky, Nikolay, Grinchuk, Tatiana
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589997/
https://ncbi.nlm.nih.gov/pubmed/33096691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102332
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