Interactions between SAP155 and FUSE-Binding Protein-Interacting Repressor Bridges c-Myc and P27Kip1 Expression

Oncogenic c-Myc plays a critical role in cell proliferation, apoptosis, and tumorigenesis, but the precise mechanisms that drive this activity remain largely unknown. P27Kip1 (CDKN1B) arrests cells in G1, and SAP155 (SF3B1), a subunit of the essential splicing factor 3b (SF3b) subcomplex of the spli...

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Bibliographic Details
Published in:Mol Cancer Res
Main Authors: Matsushita, Kazuyuki, Tamura, Mai, Tanaka, Nobuko, Tomonaga, Takeshi, Matsubara, Hisahiro, Shimada, Hideaki, Levens, David, He, Liusheng, Liu, Juhong, Yoshida, Minoru, Nomura, Fumio
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589523/
https://ncbi.nlm.nih.gov/pubmed/23594796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0673
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